Friday, February 12, 2016

Silicon Biosystems Menarini, Macrogen Partner on Genomic Cancer Assays – Genetic Engineering & Biotechnology News

Silicon Biosys­tems Menarini and Macrogen claimed today they will certainly companion to co-make health care assays and procedures with precision medication in cancer.

The firms claimed their collaboration would certainly combine Silicon Biosystems’ DEPArray™ digital-sorting technology along with Macrogen’s whole-genome, whole-exome, and targeted sequencing capabilities, along with the objective of creating CLIA-certified genomic cancer assays.

DEPArray is created to willpower cellular heterogeneity of formalin-fixed paraffin-embedded (FFPE) biopsies and fine-needle aspiration (FNA) samples. According to Silicon Biosystems, DEPArray is capable of delivering 100% pure cancer- and tumor-bad regulate cells—also as others essential cellular elements such as tumor-infiltrating lymphocytes—from FFPE tumor samples.

“Pure cells give exact answers concerning all of sorts of genomic variant and instability from the degree of targeted cancer panels up to the whole-genome level, making DEPArray sorting and sequencing an unparalleled device with precision patient stratification,” Silicon Biosystems head of state and CEO Giuseppe Giorgini claimed in a statement. “Via DEPArray sorting, we can easily suggestions rescue samples along with a fairly reduced variety of tumor cells, such as FNA and low-cellularity FFPE samples.

A wholly possessed subsidiary of the Menarini Group, Silicon Biosystems Menarini is based in San Diego and Bologna, Italy.

Macrogen, based in Seoul, South Korea, is anticipated to give technical assist with the somatic variant analysis of cancer cells Via its next-generation sequencing knowledge also as its health care study capabilities. The business is currently operating 2 units (twenty instrument units) of Illumina’s HiSeq X Ten, supplying whole-genome sequencing program worldwide. Macrogen additionally has actually a CLIA-certified laboratory, MCL, in Rockville, MD.

Macrogen Chairman Jeong-Sun Seo, M.D., Ph.D., added, “This collaboration in between Macrogen and Silicon Biosystems Menarini with the improvement of tumor-cell-individual cancer somatic variants analysis will certainly delivering the crucial incentive of precision medication to cancer patients in urgent demand sooner compared to we expected.” 

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